Astronauts Matthew Dominick, Michael Barratt and Jeanette Epps publicly discussed their spaceflight on Friday for the first time since returning from the International Space Station on October 25.
They spent almost eight months in orbit, longer than expected because of all the trouble with Boeing's Starliner crew capsule and rough weather, including Hurricane Milton.
Soon after their SpaceX capsule splashed down in the Gulf of Mexico off the Florida coast, the three were taken to a hospital in nearby Pensacola along with Russian cosmonaut Alexander Grebenkin, who launched with them back in March.
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One of the Americans ended up spending the night there for an undisclosed "medical issue".
NASA declined to say who was admitted to hospital or why, citing medical privacy.
When asked at Friday's news conference which one had been sick, the astronauts refused to comment.
Barratt, a doctor who specialises in space medicine, declined to even describe the symptoms that the unidentified astronaut had.
"Spaceflight is still something we don't fully understand," said Barratt, the only member of the crew who had flown in space before.
"We're finding things that we don't expect sometimes.
"This was one of those times and we're still piecing things together on this."
Epps said everyone was different in how they responded to space - and gravity.
"That's the part that you can't predict," she said.
"Every day is better than the day before."
Dominick said little things such as sitting comfortably in a hard chair took several days to get used to once he returned.
He said he didn't use the treadmill during his time in space, as part of an experiment to see what equipment might be pared on a long trip to Mars.
The first time he walked was when he got out of the capsule.
The two astronauts who served as test pilots for Boeing's Starliner - Butch Wilmore and Suni Williams - will remain at the space station until February, flying back with SpaceX.
Starliner returned empty in September.
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